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Respond  to your  colleagues by comparing the differential diagnostic features of the  disorder you were assigned to the diagnostic features of the disorder  your colleagues were assigned.NOTE: Positive comment (bellow is attached the sleep disorder assigned to me)Main PostSubstance /Medication Induced Sexual Dysfunction (SMISD)The purpose of this discussion is to  explain the diagnostic criteria for SMISD, and evidence-based  psychotherapy and psychopharmacologicaltreatment for SMISD. I will be supporting these  treatments and diagnostic criteria with learning course resources and  other academic resources. Thediagnosis of SMISD is when there is evidence of  substance intoxication or withdrawal that is apparent from the history  physical examination or laboratoryresults. The sexual dysfunction SMISD occurs soon  after significant substance intoxication or withdrawal, or after  exposure to a medication or a change inmedication use. Some examples of substances and  medications that cause SMISD are alcohol amphetamines or related  substances, cocaine, opioids,sedatives-hypnotics, anxiolytics, and other known or  unknown substances (Sadock et al., 2014). Almost every pharmacological  agent, especially those in thepsychiatry field have been associated with an effect  on sexuality. In men these effects include low sex drive, erectile  failure, low volume of ejaculate, anddelayed or retrograde ejaculation. In women there is  decreased sex drive, decreased vaginal lubrication, inhibited, or  delayed orgasm and decreased orabsent vaginal contractions may occur. Drugs may also  enhance the sexual responses and increase the sex drive, but this is  less common than adverseeffects (Sadock et al., 2014).Diagnostic criteriaThe diagnostic criteria for SMISD requires  that a significant disturbance in sexual function is predominant in the  clinical picture. There SMISD must beevident from the history, physical examination, or  laboratory findings of a significant sexual dysfunction during or soon  after substance intoxication orwithdrawal or after exposure to her medication. The  involved medication can produce sexual dysfunction symptoms. In  addition, the dysfunction must notbe a result of another dysfunction that is not drug-  induced must not occur during delirium and must cause clinically  significant distress in the client(Association, 2015).Psychopharmacology and Psychotherapy for SMISDSMISD can be treated by pharmacologic or  psychotherapy or both. Some classes of medication that can cause sexual  dysfunction antipsychotics. Theprevalence of low libido and problems with orgasm in  patients treated with antipsychotics regardless of sex is 54.2% and  41.7% respectively. A widelyaccepted mechanism underlying antipsychotic associated  sexual dysfunction is dopamine D2 receptor antagonism. This causes high  prolactin levels, whichcan subsequently lead to a variety of sexual problems  including erectile dysfunction, ejaculatory disturbances and  gynecomastia in men, amenorrhea, andvaginal dryness in woman. Also, low libido,  anorgasmia, and galactorrhea in both sexes. Some other medications that  cause sexual dysfunction areantipsychotics, antiparkinsonian drugs,  anticholinergics, antiepileptics, muscle relaxants, cannabis, opioids  and anti-anxiety drugs (Downing et al., 2019).Psychopharmacological treatments:Dose reduction or abstinenceSwitching to a prolactin sparing antipsychotic example Aripiprazole, Olanzapine and QuetiapineAugmenting with Aripiprazole.Adding Phosphodiesterase inhibitors specifically to treat Ed, PDE-5 inhibitors like Sildenafil can be used.Androgen therapy for male and female.Bupropion and some second-generation antipsychotics.Testosterone replacement and low  hepatic impact medications, H1 receptor antagonism with allergic  antihistamine use improves ED.Alprostadil and injectable medications Edex, MUSE and Brevital.Anti-depressants can be used for treating phobic sex.Trazodone can be used to increase nocturnal erections (Razdan et al., 2017).PsychotherapyDual-sex therapyHypnotherapyBehavior therapyMindfulness in cognitive techniqueGroup therapySpecific techniques and exercisesAnalytically oriented sex therapy (Sadock et al., 2014)ConclusionClinicians need to be more vigilant about  antipsychotic- associated sexual dysfunction and available treatment  options, because these adverse effectscan affect a patient’s quality of life and adherence  to anti-psychotic medication (Downing et al., 2019). Maintaining good  sexual health and function isespecially important in these patients to help improve  their mood, quality of life and medication compliance. The specific  aspect of sexual function that isaffected by psychiatric drugs is often ambiguous when  described in current literature. Broad questionnaires like the Arizona  Sexual Experience Scale can beused to evaluate many components of sexual health (Razdan et al., 2017).ReferencesAssociation, A. P. (2015). Dsm-5® (5th ed.). American Psychiatric Association.Downing, L., Kim, D. D., Procyshyn, R. M., & Tibbo, P. (2019). Management of sexual adverseeffects induced by atypical antipsychotic medication. Journal of Psychiatry andNeuroscience, 44(4), 287–288. https://doi.org/10.1503/jpn.190053Razdan, S., Greer, A. B., Patel, A., Alameddine, M., Jue, J. S., & Ramasamy, R. (2017). Effectof prescription medications on erectile dysfunction. Postgraduate Medical Journal,94(1109), 171–178. https://doi.org/10.1136/postgradmedj-2017-135233Sadock, B. J., Sadock, V. A., & Pedro, R. M. (2014). Kaplan and sadock’s synopsis ofpsychiatry: Behavioral sciences/clinical psychiatry (11th ed.). Lww.

 
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